ChromasPro适用于测序项目多达几个碱基,以及基本的序列编辑和分析。
具体功能如下:
以应用生物系统、Staden色谱图(SCF)、MegaBace (esd)、FASTA、EMBL、GenBank、SwissProt,、GenPept、GCG RSF和纯文本格式打开和保存序列。
将重叠序列组装一致,自动显示含糊不清的序列并编辑。
用高质量数据自动消除低质量序列并提高序列集合。
查看检测基因型文件。
生成限制位点和片段图,并且列举切割、无切割和片段。
染色体图开放阅读框,借助G+C框架图,点击一下即可翻译ORFs。
打印色谱图,限制位点和片段图,并且打开阅读框架图。
执行核苷和蛋白质BLAST,通过NCBI网站搜索。
通过ClustalW的界面执行多序列。
逆向&补充序列和色谱图。
通过准确匹配或最佳队列搜索序列。
当编辑核苷酸系列时显示翻译。
执行反向翻译和标出核苷酸退化。
划分蛋白质的亲水性和抗原性。
复制色谱图截面的图形粘贴到文档或演示文件中。
ChromasPro is a practical tool for the users who need to manage multiple DNA sequencing projects. You can use this program to import the sequence details from multiple programs and file types. DNA sequencing allows biologists and other specialists to find out the exact order of nucleotides in a DNA molecule. The process can be completed by using various methods and applications that aim to increase the accuracy. This program aims to provide you with the required tools for analysing the imported sequences and editing the data in order to improve the sequence assembly. It is also able to detect overlapping sequences in order to display the ambiguities.
The interface is simple and allows you to quickly create a project and import the sequences that you need to analyze. Once loaded, you can assemble the sequences into contigs, edit the consensus file and export the entire alignment.
An important tool is the Restriction Analysis which enables you to search for certain elements in the nucleotide sequence. The program includes multiple databases of restriction enzymes and allows you to add new items by entering the recognition data.
Besides analyzing the nucleotide structure, the application is capable of formatting the data in order to easily publish your results or share them with other colleagues. Thus, you can export the sequence as a PDF or plain text file with minimum effort.
ChromasPro has the following features:
Open and save sequences in Applied Biosystems, Staden Chromatogram (SCF), MegaBace (.esd), 454 SFF, FASTA, FASTQ, EMBL, GenBank, SwissProt, GenPept, GCG RSF and plain text formats.
Assemble overlapping sequences into a consensus and automatically display ambiguities for editing.
Use quality data to automatically remove low quality sequence and improve sequence assembly.
View Genescan genotype files.
Generate restriction site and fragment maps, and list cutters, non-cutters and fragments.
Map open reading frames, aided by a G+C frame plot, and translate ORFs with one click.
Print chromatograms, restriction site and fragment maps, and open reading frame maps.
Perform nucleotide and protein BLAST searches through the NCBI web site.
Perform multiple alignments by interfacing with ClustalW.
Reverse & complement sequences and chromatograms.
Search for sequences by exact matching or optimal alignment.
Display translations when editing nucleotide sequences.
Perform reverse translations and plot nucleotide degeneracy.
Plot hydrophilicity and antigenicity of proteins.
Copy an image of a chromatogram section for pasting into documents or presentations.
OS : Windows XP, Vista, 7 and 8
Language : English
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